{"product_id":"9783319403458","title":"Cardiovascular Safety in Drug Development and Therapeutic Use","description":"\u003cp\u003eAt a time when the field of cardiac safety is going through important changes, this unique book provides the rationale for, and cutting-edge explanations of, new regulatory landscapes that will likely govern cardiac safety assessments globally for the foreseeable future.  Exposure-response modeling is already being accepted by regulatory agencies in lieu of the traditional Thorough QT\/QTc Study, and the Comprehensive \u003ci\u003ein vitro \u003c\/i\u003eProarrhythmia Assay initiative is well under way.\u003c\/p\u003e\n\nDevelopments in the field of cardiovascular safety are also described and discussed in the book.  These include the search for more efficient ways to exonerate new drugs for type 2 diabetes from an unacceptable cardiovascular liability, how best to address off-target blood pressure increases induced by noncardiovascular drugs, and the continued evolution of the discipline of Cardio-oncology.\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e“a resource that will likely serve as a standard for years to come” \u003c\/p\u003e\u003cp\u003e- Dr Jonathan Seltzer\u003c\/p\u003e\u003cp\u003e\u003ci\u003eTherapeutic Innovation \u0026amp; Regulatory Science\u003c\/i\u003e, 2017;51(2):180\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e“I have no hesitation in recommending this book as a valuable reference source” \u003c\/p\u003e\u003cp\u003e- Dr Rashmi Shah\u003c\/p\u003e\u003cp\u003e\u003ci\u003eJournal for Clinical Studies\u003c\/i\u003e, 2017;9(1):62-63\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePublication Year: \u003c\/strong\u003e2017\u003cbr\u003e\u003cstrong\u003eImprint: \u003c\/strong\u003eSpringer International Publishing\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003eFormat: H\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003eWeight (Gram): 7276\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"J. Rick Turner","offers":[{"title":"Default Title","offer_id":41265646502066,"sku":"9783319403458","price":171.59,"currency_code":"SGD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0502\/5382\/4178\/products\/3319403451.01_SCLZZZZZZZ.jpg?v=1636021783","url":"https:\/\/readabook.store\/products\/9783319403458","provider":"READABOOK BY ALKEM","version":"1.0","type":"link"}