Selected Papers Of Frederick Sanger (With Commentaries)

This important volume is mainly concerned with the development of methods for “sequencing” — that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.

Format: Hardcover
No of Pages: 676
Imprint: World Scientific
Publication date: 19960801
Series: World Scientific Series In 20th Century Biology